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[Features of DNA repair during chronic exposure to mutagenic factors]
A B Semov1, S N Ptitsina, N Iu Semova
1Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow.
Radiatsionnaia Biologiia, Radioecologiia
|July 1, 1997
Abstract:
Long-time in vivo influence of chemical mutagens in low doses can decrease the level of unscheduled DNA synthesis (UDS) induced in human as well as in laboratory mammals. The phenomenon under investigation is not specific neither for chronically acting mutagens nor for challenging agent. A decrease in UV- and gamma-ray-induced UDS was registered after chronic irradiation in plant populations and also in Chernobyl ameliorators and inhabitants of radioactively contaminated regions. The observed effect seems to have general biological character.