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Polyester as a bioimplantable material

J S Yager1, T Chaglassian

  • 1The Plastic Surgery Center, New York, NY 10032, USA.

Annals of Plastic Surgery
|May 26, 1998
PubMed
Summary
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Polyester, a Food and Drug Administration-approved material, shows promise as a bioimplantable alternative. Engineered polyester textiles demonstrated controlled tissue ingrowth and did not obscure mammogram interpretation.

Area of Science:

  • Biomaterials Science
  • Textile Engineering
  • Medical Device Development

Background:

  • Silicone gel implants face controversy, driving demand for alternative bioimplantable materials.
  • Polyester is a Food and Drug Administration-approved prosthetic material with a history of safe use in vascular grafts.
  • Polyester's biocompatibility and potential for engineered fibrous ingrowth make it a candidate for novel implant applications.

Purpose of the Study:

  • To evaluate medical-grade polyester in woven and fibrous forms as a potential bioimplantable material.
  • To engineer polyester textiles to influence differential fibrous tissue ingrowth.
  • To assess the histological, mechanical, and imaging properties of polyester implants.

Main Methods:

  • Medical-grade polyester implants (3-cm2 diskettes) were created in four combinations of weave and fiber layers.

Related Experiment Videos

  • Implants were placed in dorsal pockets of 12 New Zealand White rabbits for 1, 3, and 6 months.
  • Histology, capsular thickness, tissue ingrowth, mammogram imaging, weight ratios, and tensile strength were analyzed.

    • Main Results:

    • Polyester implants demonstrated varying degrees of fibrous tissue ingrowth based on material configuration.
    • Histological analysis confirmed tissue integration without significant adverse reactions.
    • Mammograms taken through the polyester implants showed no obscuration of interpretation.
    • Weight ratios and tensile strength were determined for material characterization.

    Conclusions:

    • Engineered polyester textiles offer a viable alternative for bioimplantable devices, with tunable tissue ingrowth properties.
    • Polyester exhibits good biocompatibility and does not interfere with mammographic imaging.
    • Further research into polyester-based implants could lead to new options in reconstructive and augmentation surgery.