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[Acne comedonica following radiation therapy]

S Karrer¹, C B Schäfer, M Allgäuer

¹Dermatologische Klinik und Poliklinik, Universität Regensburg.

Deutsche Medizinische Wochenschrift (1946)

|May 28, 1998

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Radiation therapy for breast cancer can cause acne comedonica, a rare skin side effect. Topical treatments like benzoyl peroxide and erythromycin effectively cleared these lesions, with no recurrence after one year.

Area of Science:

Oncology
Dermatology
Radiation Oncology

Background:

Breast cancer treatment often involves radiation therapy, which can have cutaneous side effects.
Hormonal therapies, such as goserelin, are also used in breast cancer management.
Understanding treatment-related side effects is crucial for patient care.

Observation:

A patient developed acne comedonica localized to radiation fields after breast cancer treatment.
Lesions appeared weeks after completing radiation therapy and initiating goserelin.
The comedones were confined to the irradiated areas of the left breast and sternum.

Findings:

The clinical diagnosis was acne comedonica secondary to radiation therapy.
Local treatment with benzoyl peroxide gel (5%) and erythromycin cream (2%) was initiated.

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Skin lesions showed significant improvement within weeks and complete resolution in 3 months.

Implications:

Acne comedonica is a rare but notable side effect of radiation therapy.
While asymptomatic, these lesions can cause cosmetic concerns for patients.
Effective management involves topical comedolytic agents, offering a favorable prognosis.