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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography
Published on: December 2, 2022
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Endoresection of choroidal melanoma
B Damato1, C Groenewald, J McGalliard
1Ocular Oncology Service, St Paul's Eye Unit, Royal Liverpool University Hospital.
The British Journal of Ophthalmology
|May 29, 1998
Summary
Endoresection is a viable surgical option for choroidal melanoma, retaining 90% of eyes with good visual outcomes. Further follow-up is needed to confirm long-term tumor control rates.
Area of Science:
- Ophthalmology
- Surgical Oncology
- Medical Technology
Background:
- Choroidal melanoma presents a significant challenge in ocular oncology.
- Surgical interventions aim to preserve vision and prevent metastasis.
Observation:
- This study reports on 52 cases of endoresection for choroidal melanoma.
- The technique involves complex intraocular maneuvers including vitrectomy and tumor excision.
- Complications included retinal detachment (16 eyes) and cataract (25 eyes).
Findings:
- 90% of eyes were retained after primary endoresection.
- Visual acuity outcomes varied, with some patients retaining good vision.
- No local tumor recurrence was observed, though one patient died of metastatic disease.
Implications:
- Endoresection offers a vision-sparing alternative to radiotherapy for certain choroidal melanomas.
- Tumor location influences the potential to conserve central vision or temporal field.
- Long-term efficacy of endoresection for tumor control requires extended follow-up.
