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Related Experiment Videos

Biomarkers, screening and ethics

D Koh1, J Jeyaratnam

  • 1Department of Community, Occupational and Family Medicine, National University of Singapore, Republic of Singapore. cofkohd@nus.sg

Occupational Medicine (Oxford, England)
|May 30, 1998
PubMed
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Biomarker technology advances impact occupational health ethics and practice. Validated biomarkers aid in worker safety and health, but unvalidated tests require regulatory oversight to prevent discrimination.

Area of Science:

  • Occupational Health
  • Biomarker Technology
  • Medical Ethics

Background:

  • Scientific advances, particularly in biomarker technology, are significantly influencing occupational health practices and ethical considerations.
  • Biomarkers are integral to occupational health, utilized in pre-employment screening for preventive and predictive purposes.

Purpose of the Study:

  • To explore the ethical implications of using biomarkers in occupational health.
  • To discuss the application of biomarkers in pre-employment, exposure, and effect screening.
  • To address the need for updated ethical guidelines and regulatory oversight for biomarker use.

Main Methods:

  • Review of current applications of biomarkers in occupational health.
  • Analysis of preventive and predictive testing strategies.
Keywords:
Genetics and Reproduction

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  • Discussion of ethical dilemmas related to individual benefit versus employer needs.

    • Main Results:

    • Biomarkers are used for pre-employment screening to prevent accidents and predict illness risk.
    • Screening can identify susceptible workers for hazardous environments or those likely to incur high healthcare costs.
    • Biomarkers of exposure or effect are used for screening among exposed workers.

    Conclusions:

    • Physicians should initiate screening for biomarkers of effect to prevent illness onset.
    • Ethical guidelines must be updated to reflect technological and societal advances.
    • Regulatory bodies are necessary to ensure the accuracy, effectiveness, and non-discriminatory use of unvalidated biomarkers.