Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Addiction: a new paradigm

R L DuPont1

  • 1Institute for Behavior and Health, Inc., Rockville, MD 20852, USA.

Bulletin of the Menninger Clinic
|May 30, 1998
PubMed
Summary
This summary is machine-generated.

Addiction stems from the brain

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biology and the environment-rethinking demand reduction.

Journal of addictive diseases·2000
Same author

Impairment in pure and comorbid generalized anxiety disorder and major depression at 12 months in two national surveys.

The American journal of psychiatry·1999
Same author

Efficacy, safety, and tolerability of venlafaxine extended release and buspirone in outpatients with generalized anxiety disorder.

The Journal of clinical psychiatry·1999
Same author

Twelve-step and mutual-help programs for addictive disorders.

The Psychiatric clinics of North America·1999
Same author

The origins of the Minnesota model of addiction treatment--a first person account.

Journal of addictive diseases·1999
Same author

Examining the debate on the use of medical marijuana.

Proceedings of the Association of American Physicians·1999

Area of Science:

  • Neuroscience and behavioral science

Background:

  • The traditional addiction model attributed substance use disorders to ignorance, unhappiness, or lack of opportunity.
  • Physical dependence was considered the primary driver of continued use despite negative consequences.

Purpose of the Study:

  • To introduce and elaborate on the new reward-based paradigm of addiction.
  • To contrast this new model with the older view of addiction.

Main Methods:

  • Conceptual analysis and synthesis of existing addiction research.
  • Comparison of the older and newer theoretical frameworks of addiction.

Main Results:

  • The new paradigm emphasizes the powerful brain reward associated with addictive behaviors.
  • Potential addicts actively seek this reward, often disregarding risks.

Related Experiment Videos

  • Physical dependence and withdrawal are considered secondary to the primary role of reward.
  • Conclusions:

    • Addiction is fundamentally driven by the brain's powerful reward system.
    • This new understanding necessitates a shift in addiction prevention, treatment, and policy.
    • Medical interventions, including those with controlled substances, must align with this reward-centric model.