Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatitis C-associated autoimmune disorders

R W McMurray1

  • 1Department of Medicine, University of Mississippi Medical Center, Jackson, USA.

Rheumatic Diseases Clinics of North America
|June 2, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of chronic exposure to DDT and TCDD on disease activity in murine systemic lupus erythematosus.

Lupus·2009
Same author

Hepatitis C virus and systemic lupus erythematosus.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2008
Same author

Osteoarthritis of the sternoclavicular joint.

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2008
Same author

Estrogen and progesterone modulate monocyte cell cycle progression and apoptosis.

American journal of reproductive immunology (New York, N.Y. : 1989)·2003
Same author

Sex hormones in the pathogenesis of systemic lupus erythematosus.

Frontiers in bioscience : a journal and virtual library·2001
Same author

Prolactin in murine systemic lupus erythematosus.

Lupus·2001

Hepatitis C virus (HCV) infection frequently triggers autoimmune diseases through immune responses. Patients with HCV-related autoimmune conditions may benefit from immunosuppressive treatments.

Area of Science:

  • Immunology
  • Hepatology
  • Rheumatology

Background:

  • Hepatitis C virus (HCV) infection is linked to various autoimmune conditions.
  • The immune response to HCV involves autoantibodies, immune complex deposition, and cryoglobulinemia.
  • Associated conditions include antiphospholipid antibody syndrome, rheumatoid arthritis, SLE, PM/DM, thyroid disease, and sicca symptoms.

Purpose of the Study:

  • To review the association between Hepatitis C virus infection and autoimmune manifestations.
  • To discuss the immunological mechanisms underlying HCV-related autoimmunity.
  • To explore treatment strategies for HCV-associated autoimmune diseases.

Main Methods:

  • Literature review of studies investigating HCV and autoimmune diseases.
  • Analysis of immunological responses in HCV infection.

Related Experiment Videos

  • Evaluation of treatment outcomes for HCV-related autoimmune conditions.

    • Main Results:

    • HCV infection commonly leads to autoantibody production and immune complex-mediated diseases.
    • Cryoglobulinemia, vasculitis, glomerulonephritis, and neuropathy are frequent complications.
    • HCV patients exhibit high rates of sicca symptoms and potential for lymphoproliferative malignancies.

    Conclusions:

    • HCV infection is a significant trigger for a spectrum of autoimmune disorders.
    • Immunosuppressive therapy, including standard agents and interferon, shows promise in managing these conditions.
    • Further research is needed to optimize treatment protocols for HCV-related autoimmune diseases.