Related Experiment Video
Updated: Aug 15, 2026

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
Cyanonitrosylmetallates as potential NO-donors
J Oszajca1, G Stochel, E Wasielewska
1Department of Inorganic Chemistry, Jagiellonian University, Kraków, Poland.
Abstract:
The [M(CN)xNOy]n- complexes (where M = Cr(I), Mn(I), Mn(II), Fe(I), Fe(II), Fe(III)) were studied as potential NO-donors using both pharmacological and theoretical semi-empirical methods. Only iron complexes appeared to be pharmacologically active. The quantum chemical calculations indicated that these complexes have the highest predisposition to undergo a nucleophilic attack followed by the NO+ release. The results allowed us to interpret the metabolism of the [M(CN)xNOy]n- complexes in terms of the NO(+)-donation.
Related Concept Videos
Properties of Organometallic Compounds
Aldehydes and Ketones with HCN: Cyanohydrin Formation Overview
2° Amines to N-Nitrosamines: Reaction with NaNO2
Aldehydes and Ketones with HCN: Cyanohydrin Formation Mechanism
EDTA: Auxiliary Complexing Reagents
Masking and Demasking Agents
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on the metal...

