[Functional characteristics of the Langerhans islets in type I gastric heterotopic pancreas]

In a retrospective five years study of gastric wall tumors, we selected the type 1 heterotopic pancreas. The assessment of fibrosis and inflammatory infiltrate were performed. Also the immunohistochemical evaluation with monoclonal antibodies for insulin, glucagon, p substance, somatostatin, gastrin and antichimotrypsin. None of the case showed remarkable fibrosis or inflammatory infiltrate. All the Langerhans's islets stained positive for 2 or 3 hormones, gastrin and antichimotrypsin were always negative. These findings are comparable with others previously reported, but no cases of evaluation of islet's gastrin exist in the literature reviewed.