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Progress toward understanding the molecular mechanisms of neurotrophic factor signalling
1Department of Biochemistry, School of Medical Sciences, University of Bristol, UK.
Cellular Signalling
|June 2, 1998
Abstract:
Understanding the mechanism of action of the neurotrophic factors is central to unravelling of the mysteries of some of the neurodegenerative disorders. In this review we will discuss recent advances in our understanding of neurotrophic factor signalling in primary cultured neurons, in particular those from the superior cervical and dorsal root ganglia, as well as cerebellar granule cells, cortical neurons and oligodendrocytes.