Necrotizing enterocolitis after gastroschisis repair: a preventable complication?

¹Department of Paediatric Surgery and Neonatology, Leeds General Infirmary, England.

|June 2, 1998

Summary

Feeding infants expressed breast milk after gastroschisis repair may protect against necrotizing enterocolitis (NEC). Exclusively formula-fed infants had a higher incidence of NEC compared to those receiving breast milk.

Area of Science:

Neonatal surgery
Pediatric gastroenterology
Infant nutrition

Background:

Necrotizing enterocolitis (NEC) is a significant cause of morbidity in infants following gastroschisis repair.
NEC occurs more frequently in preterm infants fed formula compared to breast milk.

Purpose of the Study:

To investigate whether maternal expressed breast milk (EBM) protects infants undergoing gastroschisis repair from developing NEC.

Main Methods:

Retrospective analysis of 60 newborns with gastroschisis treated between 1990 and 1996.
Data collected included feeding regimens and NEC episodes.
Infants were categorized by feeding: exclusively EBM, EBM and formula, or exclusively formula.

Main Results:

Of 54 infants without mortality, 8 (15%) developed NEC.
No NEC cases occurred in 12 infants exclusively fed EBM.
NEC developed in 1 of 19 (5%) receiving EBM and formula, and 7 of 23 (30%) fed solely formula (P < .02).

Conclusions:

Maternal expressed breast milk feeding may offer protection against NEC in infants after gastroschisis repair.
Formula feeding is associated with a higher risk of NEC in this population.

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Area of Science:

Background:

Purpose of the Study:

Main Methods:

Main Results:

Conclusions:

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