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[Neonatal sepsis caused by Streptococcus agalactiae. What should be done?]
R Montero Alonso1, F Barbadillo Izquierdo, S Ansó Oliván
1Sección Neonatal (Servicio de Pediatría), Hospital General Yagüe, Burgos.
Anales Espanoles De Pediatria
|June 3, 1998
Summary
Group B Streptococcus (GBS) causes neonatal sepsis. Intrapartum treatment of at-risk mothers and early urine testing in newborns effectively reduced GBS sepsis incidence and mortality.
Area of Science:
- Neonatal infectious diseases
- Bacteriology
- Obstetrics
Context:
- Group B Streptococcus (GBS) is a primary cause of neonatal sepsis, often transmitted vertically from maternal colonization.
- Preventative strategies focus on maternal screening and treatment to mitigate neonatal infection risks.
Purpose:
- To review GBS sepsis and present a protocol for managing at-risk pregnancies and newborns.
- To evaluate the effectiveness of intrapartum maternal treatment and early neonatal urine screening for GBS detection.
Summary:
- The study implemented a protocol involving intrapartum treatment for high-risk pregnant women and routine early urine latex particle testing for GBS in newborns.
- Over a decade, GBS sepsis incidence was 0.9/1,000, with a 10.5% fatality rate, showing an increasing trend in GBS prevalence.
Impact:
- The combined strategy of maternal intrapartum treatment and neonatal early urine screening resulted in low GBS sepsis incidence and mortality rates.
- This approach effectively identifies carrier mothers and prevents false negatives, enhancing neonatal protection against GBS infection.