Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A technique for the quantitative evaluation of dose distributions

D A Low1, W B Harms, S Mutic

  • 1Mallinckrodt Institute of Radiology, Division of Radiation Oncology, St. Louis, Missouri 63110, USA. low@castor.wustl.edu

Medical Physics
|June 3, 1998
PubMed
Summary

A new gamma index method unifies dose distribution comparisons in radiation therapy, providing a quantitative measure of calculation accuracy. This technique ensures treatment planning systems meet acceptance criteria for precise patient care.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute impact of aerobic exercise on local cutaneous thermal hyperaemia.

Microvascular research·2022
Same author

The effects of exercise training in the cold on cerebral blood flow and cerebrovascular function in young healthy individuals.

Autonomic neuroscience : basic & clinical·2022
Same author

An Adaptive Low-Rank Modeling-Based Active Learning Method for Medical Image Annotation.

Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research·2021
Same author

Oxynet: A collective intelligence that detects ventilatory thresholds in cardiopulmonary exercise tests.

European journal of sport science·2020
Same author

A mechanistic study of the tremor associated with epidural anaesthesia for intrapartum caesarean delivery.

International journal of obstetric anesthesia·2020
Same author

McSART: an iterative model-based, motion-compensated SART algorithm for CBCT reconstruction.

Physics in medicine and biology·2019

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Radiotherapy Treatment Planning

Background:

  • Commissioning 3D treatment planning systems necessitates comparing measured and calculated dose distributions.
  • Existing methods like superimposed isodoses, dose-difference, and distance-to-agreement (DTA) have limitations in comprehensively assessing accuracy.

Purpose of the Study:

  • To develop a unified technique for comparing dose distributions that provides a quantitative measure of calculation accuracy.
  • To introduce the gamma index as a method to assess the acceptability of dose calculations against predefined criteria.

Main Methods:

  • Developed a multidimensional distance measure in dose and spatial coordinates, scaled by acceptance criteria.
  • Defined the gamma index as the minimum radial distance in dose-distance space between measurement and calculation points.

Related Experiment Videos

  • Utilized a 6 MV beam penumbra example to illustrate the gamma index application.
  • Main Results:

    • The gamma index quantitatively indicates calculation accuracy, with gamma > 1 signifying failure to meet acceptance criteria.
    • This method provides a unified approach, overcoming limitations of previous dose-difference and DTA comparisons.
    • The gamma index offers a clear numerical measure for display and analysis of dose distribution accuracy.

    Conclusions:

    • The gamma index is an effective tool for quantitatively assessing the accuracy of dose calculations in radiotherapy.
    • This method facilitates the commissioning and quality assurance of 3D treatment planning systems.
    • The gamma index ensures that treatment planning calculations meet predefined acceptance criteria for patient safety and treatment efficacy.