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Androgens and women's health
1Center for Health Studies, Inc., Cleveland, Ohio 44122, USA.
International Journal of Fertility and Women'S Medicine
|June 3, 1998
Summary
Androgenic disorders, common in women, cause acne, hirsutism, and hair loss. Polycystic ovary syndrome (PCOS) adds menstrual issues and obesity, increasing risks for diabetes and heart disease.
Area of Science:
- Endocrinology
- Dermatology
- Women's Health
Background:
- Androgenic disorders affect 10-20% of women, manifesting as acne, hirsutism, and alopecia.
- Polycystic ovary syndrome (PCOS) is a subgroup with anovulation, menstrual irregularities, and obesity.
- These conditions are linked to insulin resistance, Type II diabetes, and adverse lipid profiles.
Purpose of the Study:
- To review the clinical presentation, diagnosis, and management of androgenic disorders in women.
- To highlight the broader health implications beyond skin and menstrual changes.
- To emphasize the importance of physician understanding for effective patient care.
Main Methods:
- Review of clinical signs including acne, hirsutism, alopecia, and acanthosis nigricans.
- Diagnostic criteria involving measurement of serum androgens (free testosterone), prolactin, and FSH.
- Discussion of treatment strategies including oral contraceptives and anti-androgen medications.
Main Results:
- Diagnosis may involve elevated androgens or increased end-organ sensitivity.
- Treatment can successfully control skin symptoms and stabilize hair loss.
- Many women face challenges in seeking and receiving adequate medical help.
Conclusions:
- Understanding androgenic disorders is crucial for physicians to effectively manage these common conditions in women.
- Early diagnosis and comprehensive management can improve patient outcomes and quality of life.
- Addressing associated metabolic risks like insulin resistance and diabetes is essential.