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[Fascicular block and skeletal myopathies]
Summary
Skeletal myopathies often present with heart conduction abnormalities, including various fascicular blocks. Lifelong cardiological monitoring is crucial due to the risk of complete atrioventricular block.
Area of Science:
- Cardiology
- Neurology
- Genetics
Context:
- Skeletal myopathies are a group of inherited disorders affecting muscle tissue.
- Electrocardiogram (ECG) is a non-invasive diagnostic tool used to assess cardiac function.
Purpose:
- To investigate the prevalence and types of cardiac conduction abnormalities in patients with skeletal myopathies.
- To determine the prognostic implications of these abnormalities.
Summary:
- ECG findings in skeletal myopathies frequently reveal mono- and bifascicular blocks, affecting approximately 50% of cases.
- Commonly observed blocks include left anterior fascicular block, left posterior fascicular block, and right bundle branch block (RBBB).
Impact:
- The presence of these blocks indicates a potential risk for developing complete atrioventricular (AV) block.
- Prognosis for complete AV block can be poor, necessitating lifelong cardiological observation and management.