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Entomophthoromycosis in India--a 4-year study
Mycoses
|June 4, 1998
Summary
This study reports ten cases of entomophthoromycosis in Tamilnadu, primarily affecting children. Treatment with potassium iodide led to complete lesion resolution in most patients, highlighting its efficacy for this fungal infection.
Area of Science:
- Mycology
- Infectious Diseases
- Dermatology
Background:
- Entomophthoromycosis is a rare fungal infection caused by fungi in the Entomophthorales order.
- It can manifest in two main forms: basidiobolomycosis and conidiobolomycosis.
- Geographic distribution and clinical presentation vary, with distinct patterns observed in different age groups and regions.
Purpose of the Study:
- To report and analyze ten cases of entomophthoromycosis observed over four years in Tamilnadu.
- To describe the clinical characteristics and outcomes of basidiobolomycosis and conidiobolomycosis in the studied population.
- To evaluate the effectiveness of potassium iodide as a treatment for entomophthoromycosis.
Main Methods:
- Retrospective case series analysis of ten patients diagnosed with entomophthoromycosis.
- Clinical data collection including patient demographics, lesion presentation, and treatment administered.
- Assessment of treatment response and patient outcomes.
Main Results:
- Ten cases of entomophthoromycosis were identified over a four-year period.
- Eight cases were diagnosed as basidiobolomycosis, predominantly in pediatric patients.
- Two cases of conidiobolomycosis were observed in elderly individuals.
- Potassium iodide was the primary treatment used.
- Nine out of ten patients achieved complete resolution of their lesions with potassium iodide treatment.
Conclusions:
- Entomophthoromycosis, particularly basidiobolomycosis, occurs in Tamilnadu and predominantly affects children.
- Conidiobolomycosis presents in older individuals.
- Potassium iodide is an effective therapeutic agent for entomophthoromycosis, leading to high rates of complete remission.