[Scintigraphic images im primary hyperparathyroidism with 99m Tc-Tetrofosmin]

To evaluate the scintigraphy images of 99mTc-tetrofosmin in the primary hyperparathyroidism, we studied 8 patients, 5 males, with ages between 17 and 82 (median = 50) years old, and with clinical and laboratory manifestations of hyperparathyroidism (calcium metabolism and PTH elevated); parathyroid scintigraphy was realized after 20mCi (740 MBq) intravenously injection of 99mTc-tetrofosmin, and were acquired images (10, 60 and 120 min.) in a large field gamma camera. All patients were submitted to surgery. The histology of surgical specimens showed seven adenomas and one adenocarcinoma of parathyroids; the scintigraphic images showed four lesions in the inferior right lobe and four in the inferior left lobe of thyroid and have global correlation with surgical findings. There was preferential retention of the tracer in the earlier images (10 min) in all cases (100%) and in the later images (120 min.) in 5 cases (62.5%). In conclusion, the earlier images (10 min) were more diagnostic than the later in the primary hyperparathyroidism study. It is possible that other tumoral lesions have similar behavior with 99mTc-tetrofosmin.