[The evaluation of classical morphologic patterns in allergic conditions (author's transl)]

The main classical morphologic features of the allergic diseases comprise fibrinoid necrosis, tissue eosinophilia, vasculitis, capsulitis and trabeculitis in the spleen (exceptionally also in the lymph nodes) and histiocytic granulomatous reaction. The greatest diagnostic value is attributed to capsulitis and trabeculitis in the spleen and further to vasculitis and fibrinoid necrosis. The other morphologic changes, i.e. tissue eosinophilia and histiocytic granuloma are, from the point of view of differential diagnosis, of minor value. The allergic histiocytic reaction in the lymphnodes seldom exhibits a pseudotumorous pattern.