Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Transmissible spongiform encephalopathies in animals]

R Fatzer1, M Vandevelde

  • 1Nationales Zentrum für spongiforme Enzephalopathien, Institut für Tierneurologie, Bern, Schweiz.

Wiener Medizinische Wochenschrift (1946)
|June 5, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differences in Epidural Pathology between Cervical and Thoracolumbar Intervertebral Disk Extrusions in Dogs.

Journal of veterinary internal medicine·2017
Same author

Endothelin-1 Immunoreactivity and its Association with Intramedullary Hemorrhage and Myelomalacia in Naturally Occurring Disk Extrusion in Dogs.

Journal of veterinary internal medicine·2016
Same author

Neurohistological abnormalities during early porcine endotoxemia.

Acta anaesthesiologica Scandinavica·2015
Same author

Targeted surveillance for bovine spongiform encephalopathy.

The Veterinary record·2015
Same author

Multifocal ischemic brain infarctions secondary to spontaneous basilar artery occlusion in a dog with systemic thromboembolic disease.

Journal of veterinary internal medicine·2014
Same author

The fetal patient -- ethical aspects of fetal therapy.

Facts, views & vision in ObGyn·2014

Transmissible spongiform encephalopathies (TSEs) affect various animal species, with origins ranging from natural spread to contaminated feed. Diagnostic methods and control measures, like feed bans, have successfully reduced bovine spongiform encephalopathy (BSE) incidence.

Area of Science:

  • Veterinary Neurology
  • Prion Disease Research
  • Comparative Pathology

Context:

  • Transmissible spongiform encephalopathies (TSEs) are neurodegenerative diseases affecting numerous animal species globally.
  • Examples include scrapie in sheep, chronic wasting disease (CWD) in North American cervids, and transmissible mink encephalopathy (TME).
  • Bovine spongiform encephalopathy (BSE) outbreaks in Great Britain were linked to contaminated animal protein feed, subsequently spreading internationally.

Purpose:

  • To review the epidemiology and origins of various animal TSEs.
  • To outline diagnostic approaches for TSEs, including neuropathology and prion protein detection.
  • To discuss control measures implemented to mitigate TSE transmission and public health risks.

Summary:

Related Experiment Videos

  • TSEs manifest in diverse animal populations, with distinct transmission routes and origins.
  • Diagnosis relies on brain examination and identification of disease-specific prion proteins (PrPres).
  • Key control strategies involve prohibiting animal protein feeding to ruminants, significantly reducing BSE prevalence. Confiscation of infectious organs in cattle aims to protect consumers.

    • Impact:

    • Effective control measures, particularly feed bans, have demonstrably decreased BSE incidence.
    • Public health interventions, such as organ confiscation, are crucial for preventing zoonotic transmission, exemplified by the potential link between BSE and variant Creutzfeldt-Jakob disease (nvCJD).
    • Ongoing surveillance and regulatory actions are vital for managing TSEs in animal populations and safeguarding human health.