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[Sensitivity to disinfectants in certain rare micromycetes]

F Volná1, Z Jesenská

  • 1Ustav preventívnej a klinickej medicíny, Bratislava.

Epidemiologie, Mikrobiologie, Imunologie : Casopis Spolecnosti Pro Epidemiologii a Mikrobiologii Ceske Lekarske Spolecnosti J.E. Purkyne
|June 5, 1998
PubMed

Insights

Six disinfectants were tested against rare fungal strains. Alcoholic solutions, glutaraldehyde, peroxocompounds, and peroxoacetic acid showed effectiveness, while active chlorine was least effective against Scedosporium apiospermum.

Area of Science:

  • Mycology
  • Antimicrobial Efficacy
  • Fungal Pathogens

Context:

  • Rare filamentous micromycetes, including Scedosporium apiospermum, Exophiala dermatitidis, Fusarium dimerum, Fusarium moniliforme, and Stachybotrys alternans, pose significant health and environmental risks.
  • These fungi are implicated in challenging infections like ophthalmomycoses and nosocomial fungemia, and some species are known mycotoxin producers.
  • Effective disinfection strategies are crucial for controlling the spread of these opportunistic and toxigenic fungi in clinical and environmental settings.

Purpose:

  • To evaluate the efficacy of six different disinfectants against clinically and environmentally relevant filamentous micromycetes.
  • To identify the most and least effective disinfectant agents for controlling Scedosporium apiospermum, Exophiala dermatitidis, Fusarium dimerum, Fusarium moniliforme, and Stachybotrys alternans.
  • To provide data guiding the selection of appropriate disinfectants for managing infections and contamination caused by these rare fungal species.

Summary:

  • Six disinfectants were tested at recommended concentrations against strains of Scedosporium apiospermum, Exophiala dermatitidis, Fusarium dimerum, Fusarium moniliforme, and Stachybotrys alternans.
  • Most tested fungal strains demonstrated sensitivity to alcoholic solutions, glutaraldehyde-based preparations, inorganic peroxocompounds, and peroxoacetic acid.
  • The disinfectant containing active chlorine exhibited the lowest effectiveness, and Scedosporium apiospermum emerged as the most resistant fungal strain among those tested.

Impact:

  • This research identifies key disinfectants effective against specific rare fungal pathogens, informing infection control protocols in healthcare settings.
  • Findings aid in selecting appropriate agents to combat ophthalmomycoses and nosocomial fungemia caused by Scedosporium apiospermum and Fusarium species.
  • The study highlights the differential efficacy of disinfectants, guiding environmental decontamination strategies against toxigenic fungi like Stachybotrys alternans.

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