Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Custom-made root analogue titanium implants placed into extraction sockets. An experimental study in monkeys

R J Kohal1, M B Hürzeler, L F Mota

  • 1Department of Prosthodontics, Albert-Ludwigs-University, Freiburg, Germany. kohal@sun1.ukl.uni-freiburg.de

Clinical Oral Implants Research
|June 5, 1998
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In silico study of the pharmacokinetics and human and environmental toxicological analysis of cannabidiol.

Brazilian journal of biology = Revista brasleira de biologia·2025
Same author

Correction: German S3 guideline on the use of dental ceramic implants.

International journal of implant dentistry·2023
Same author

A rare case of Immunoglobulin A dominant post-infectious glomerulonephritis (IgA PIGN) in a young patient.

BMC nephrology·2022
Same author

German S3 guideline on the use of dental ceramic implants.

International journal of implant dentistry·2022
Same author

Historical development of root analogue implants: a review of published papers.

The British journal of oral & maxillofacial surgery·2019
Same author

[Skin ulcerations due to CINCA syndrome and its successful treatment with prostaglandin E<sub>1</sub>].

Zeitschrift fur Rheumatologie·2018

Custom titanium implants, mimicking tooth roots, showed successful osseointegration in monkey extraction sockets. This study supports further clinical trials for this novel CAD/CAM-based dental implant system.

Area of Science:

  • Biomaterials Science
  • Dental Implantology
  • Veterinary Dentistry

Background:

  • Custom-made implants offer personalized solutions in reconstructive dentistry.
  • Root analogue implants aim to replicate natural tooth root morphology and function.
  • Computer-aided design/computer-aided manufacturing (CAD/CAM) systems enable precise fabrication of dental prosthetics.

Purpose of the Study:

  • To clinically and histologically evaluate a novel custom-made, root analogue titanium implant.
  • To assess the osseointegration of CAD/CAM-fabricated titanium implants placed in extraction sockets.
  • To determine the bone-to-implant contact percentage in a non-human primate model.

Main Methods:

  • Titanium root analogue implants were fabricated using a CAD/CAM system based on extracted tooth replicas.

Related Experiment Videos

  • Implants were placed into extraction sockets of incisors in three Macaca fascicularis monkeys.
  • Histometric analysis was performed after 6 months of healing to measure mineralized bone-to-implant contact.

    • Main Results:

    • A mean mineralized bone-to-implant contact of 41.2% +/- 20.6% was achieved.
    • Osseointegration of the laser-copied titanium implants was demonstrated.
    • A clinical complication noted was the fracture of the buccal alveolar wall during implant placement.

    Conclusions:

    • Custom-made, laser-copied titanium root analogue implants can achieve osseointegration.
    • The findings support further clinical and experimental trials with advanced CAD/CAM equipment.
    • This novel implant system shows promise for dental applications, pending further evaluation.