Related Experiment Video
Updated: Aug 11, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
A review of the literature: transmyocardial laser revascularization
1Department of Vascular Surgery, Harbor UCLA Medical Center, Torrance 90502, USA.
Background And Objective:
Transmyocardial laser revascularization is an investigational procedure that improves chronic angina that is not amenable to other forms of therapy. The theorized mechanism is an increased supply of oxygenated blood to the myocardium via the creation of left ventricular transmural channels. The objective of this review is to facilitate an understanding of the current work published in the literature on the subject of transmyocardial laser revascularization.
Methods:
Using Melvyl Medline, all pertinent literature associated with transmyocardial laser revascularization was sought and reviewed.
Conclusion:
The research in transmyocardial laser revascularization is growing. The results of the current work in animals is conflicting with some showing a benefit from this procedure and others that refute its effectiveness. This may be the outcome of differing methodology, which has yet to be evaluated. Although the results of human trials are positive, the overall effectiveness in comparison with the conventional forms of therapy has not been addressed. It is, therefore, a procedure worthy of continued study.

