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[Structural characteristics providing for high specificity of enteropeptidase]

A G Mikhaĭlova1, L D Rumsh

  • 1Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

Summary

Enteropeptidase specificity changes due to calcium loss, leading to autolysis and a truncated enzyme form. Researchers identified cleavage sites and kinetic parameters, finding conditions to regulate this transition.

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