Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sequential changes in gas exchange following traumatic fat embolism

R M Burnstein1, J P Newell, J G Jones

  • 1University Department of Anaesthesia, Addenbrooke's Hospital, Cambridge, UK.

Anaesthesia
|June 5, 1998
PubMed
Summary

Fat embolism syndrome following a femur fracture can cause respiratory issues like shunt and ventilation/perfusion mismatch. These complications can worsen with anesthesia, highlighting the need for careful monitoring.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Does the implementation of a trauma system affect injury-related morbidity and economic outcomes? A systematic review.

Emergency medicine journal : EMJ·2024
Same author

Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype.

International journal of obesity (2005)·2017
Same author

A method for observation and enumeration of epilithic algae directly on the surface of stones.

Oecologia·2017
Same author

Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype.

International journal of obesity (2005)·2016
Same author

A mechanistic approach to modelling the formation of a drug reservoir in the skin.

Mathematical biosciences·2016
Same author

Acute Posterior Cranial Fossa Hemorrhage-Is Surgical Decompression Better than Expectant Medical Management?

Neurocritical care·2016

Area of Science:

  • Medical Physiology
  • Respiratory Medicine
  • Trauma Surgery

Background:

  • Fat embolism syndrome (FES) is a potential complication following long bone fractures, particularly of the femur.
  • FES can lead to significant respiratory compromise, including impaired gas exchange.
  • Quantifying these physiological changes is crucial for understanding disease progression and management.

Observation:

  • A young male patient with a fractured femoral shaft developed symptoms consistent with fat embolism syndrome.
  • Continuous monitoring of oxygen saturation and inspired oxygen levels was performed.
  • Ventilation/perfusion (V/Q) mismatch and shunt fraction were assessed over time.

Findings:

  • The patient exhibited significant shunt and V/Q mismatch, indicative of impaired lung function.

Related Experiment Videos

  • These respiratory abnormalities showed gradual improvement in the week post-admission.
  • A notable deterioration in gas exchange occurred after undergoing general anesthesia for femoral nailing.

    • Implications:

    • This case demonstrates the dynamic nature of respiratory compromise in FES.
    • Anesthesia and surgical intervention can acutely worsen gas exchange in FES patients.
    • Close respiratory monitoring is essential throughout the management of FES, especially around surgical procedures.