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Intracranial tuberculoma in Kuwait

N U Abdul-Ghaffar¹, M R El-Sonbaty, N A Rahman

¹Medical Department, Adan Hospital, Kuwait. naser@xtra.co.nz

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease

|June 5, 1998

Summary

Intracranial tuberculomas are treatable with a 6-week medical trial, showing significant improvement. Surgery is reserved for non-responders, but recurrence is possible. This study offers diagnostic and management guidelines for developing countries.

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Area of Science:

Neurology
Infectious Diseases
Public Health

Background:

Intracranial tuberculoma is a significant challenge in developing countries due to limited diagnostic and neurosurgical facilities.
Understanding its manifestations and treatment outcomes is crucial for effective patient management.

Purpose of the Study:

To describe the clinical features of intracranial tuberculoma in Kuwait.
To propose diagnostic and management guidelines for intracranial tuberculoma in resource-limited settings.

Main Methods:

Retrospective analysis of patients with intracranial space-occupying lesions admitted between 1987 and 1995.
Evaluation of treatment response to medical therapy and surgical intervention.

Main Results:

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Intracranial tuberculomas constituted 1.4% of space-occupying lesions; males predominated (77%).
Seizures were the most common symptom; 66.6% responded well to medical treatment within 12 weeks.
Seven patients required surgery, and recurrence was noted in some cases post-surgery.

Conclusions:

A 6-week therapeutic trial is recommended for enhancing intracranial lesions without mass effect, given non-specific imaging findings.
Stereotactic biopsy should be considered when facilities permit.
These guidelines aim to improve diagnosis and management in resource-limited regions.