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A new variant chromosomal translocation t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma

L Mitev1, S Christova, E Hadjiev

  • 1Department of Cytogenetics, Military Medical Academy, Faculty of Medicine, National Centre of Oncology, Sofia, Bulgaria.

Leukemia & Lymphoma
|June 5, 1998
PubMed

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T Cell Activation and Clonal Selection01:22

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T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...