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Excess dietary protein may not adversely affect bone

R P Heaney1

  • 1Creighton University, Omaha, NE 68178, USA.

The Journal of Nutrition
|June 18, 1998
PubMed
Summary

Adequate dietary calcium intake is crucial for skeletal health, especially when increasing protein consumption. A calcium-to-protein ratio of 20:1 (mg:g) or higher likely protects bones from potential harm caused by excess protein.

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Area of Science:

  • Nutritional Science
  • Bone Metabolism
  • Calcium and Protein Interactions

Background:

  • Insufficient protein intake negatively impacts skeletal integrity.
  • Elevated dietary protein can increase endogenous calcium excretion.
  • The body's adaptive response to protein intake is contingent on sufficient calcium availability.

Purpose of the Study:

  • To investigate the relationship between dietary protein, calcium excretion, and skeletal health.
  • To determine the critical calcium-to-protein ratio for maintaining bone health.
  • To assess the impact of varying protein and calcium intakes on skeletal outcomes.

Main Methods:

  • Analysis of endogenous calcium excretion in response to dietary protein.
  • Evaluation of calcium intake adequacy in relation to protein consumption.
  • Calculation of dietary calcium-to-protein ratios.

Main Results:

  • Increasing dietary protein leads to greater endogenous calcium excretion.
  • Adequate calcium intake mitigates the negative skeletal effects of increased protein.
  • A dietary calcium-to-protein ratio of approximately 20:1 (mg:g) appears protective for the skeleton.

Conclusions:

  • Skeletal health is compromised by insufficient protein intake.
  • Excess dietary protein does not harm the skeleton if calcium intake is sufficient.
  • Maintaining an adequate dietary calcium-to-protein ratio is essential for bone protection.

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