Extensive nodular infiltration of extra-osseous tissues in human myelomatosis. A case report

The autopsy findings of a woman with myelomatosis diagnosed half a year before her death are described. She had an IgG-lambda myeloma which initially responded to treatment. However, subsequently she developed a condition characterized by massive soft tissue involvement with increased number of plasma cells in peripheral blood. Rounded hard myeloma infiltrates were disseminated through the body, only sparing the adrenal glands and intracranial structures.