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[Rectal complications of radiotherapy]
J F Bosset1, P Bontemps, P Courvoisier
1Service de radiothérapie-oncologie, CHU Jean-Minjoz, Besançon, France.
Summary
Radiotherapy for prostate, cervix, and rectal cancers can cause late rectal morbidity in 2%-25% of patients, leading to symptoms like bleeding and ulcers. Treatment options include nutritional advice, laser therapy, formalin, and surgery.
Area of Science:
- Oncology
- Radiation Oncology
- Gastroenterology
Context:
- Radiotherapy is a common curative treatment for prostate, cervix, and rectal cancers.
- Late rectal morbidity is a significant concern following these treatments.
- Observed incidence ranges from 2% to 25% of patients.
Purpose:
- To outline the clinical manifestations of late rectal morbidity.
- To provide recommendations for clinical practice regarding management.
- To describe available treatment options for these adverse effects.
Summary:
- Late rectal morbidity presents with proctitis, strictures, bleeding, ulcers, and fistulas.
- These conditions can severely impact patient lifestyle and potentially be fatal.
- Management strategies encompass nutritional support, laser therapy, formalin application, and surgical interventions.
Impact:
- Improved patient care through evidence-based recommendations for managing radiotherapy-induced rectal complications.
- Enhanced quality of life for cancer survivors experiencing late treatment effects.
- Potential reduction in treatment-related mortality and morbidity.