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Case report: benign liver tumor with central necrosis
Journal of Clinical Ultrasound : JCU
|April 1, 1978
Summary
A previously healthy woman experienced severe abdominal pain and fever, leading to the discovery of liver lesions. Both lesions were diagnosed as focal nodular hyperplasia, a condition not typically linked to oral contraceptives.
Area of Science:
- Hepatobiliary Medicine
- Surgical Pathology
- Diagnostic Imaging
Background:
- Liver lesions, including adenomas and focal nodular hyperplasia (FNH), can present with varied clinical symptoms.
- The association between oral contraceptive use and liver tumors, particularly adenomas, is established.
- The relationship between oral contraceptives and FNH remains less clear, necessitating further investigation.
Observation:
- A 38-year-old woman presented with acute upper abdominal pain and fever.
- Imaging studies revealed a necrotizing liver lesion, with arteriography suggesting either an adenoma or FNH.
- Surgical resection of lesions in both liver lobes was performed.
Findings:
- Microscopic examination confirmed both resected liver lesions as focal nodular hyperplasia.
- While adenomas are linked to oral contraceptive use, FNH is not typically associated.
- The study identified potential increased bleeding risk in oral contraceptive users with both adenoma and FNH.
Implications:
- This case highlights the importance of accurate diagnosis of liver lesions, distinguishing between adenoma and FNH.
- It suggests a potential, though not fully established, link between oral contraceptive use and an increased bleeding risk in patients with FNH.
- Further research is warranted to elucidate the precise relationship between oral contraceptives, FNH, and hemorrhagic complications.