Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hemifacial spasm triggered by vasodilators

F Micheli1, M C Scorticati, I Radi Orueta

  • 1Department of Neurology, Hospital de Clínicas José de San Martin, UBA, Buenos Aires, Argentina.

Clinical Neuropharmacology
|June 9, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unravelling Marine Benthic Functioning Shifts Under Ocean Acidification.

Ecology letters·2026
Same author

Azimuthal Correlations within Exclusive Dijets with Large Momentum Transfer in Photon-Lead Collisions.

Physical review letters·2023
Same author

Exploring multiple stressor effects with Ecopath, Ecosim, and Ecospace: Research designs, modeling techniques, and future directions.

The Science of the total environment·2023
Same author

Measurements of the associated production of a W boson and a charm quark in proton-proton collisions at <math> </math>.

The European physical journal. C, Particles and fields·2022
Same author

Probing Charm Quark Dynamics via Multiparticle Correlations in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2022
Same author

First Search for Exclusive Diphoton Production at High Mass with Tagged Protons in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2022
Same journal

Characterization of Propranolol Use and Outcomes in Traumatic Brain Injury at a Level I Trauma Center.

Clinical neuropharmacology·2026
Same journal

Review of Medications That Reduce Neurological Deficits in Patients With Traumatic Brain Injury.

Clinical neuropharmacology·2026
Same journal

Pre-Existing Peak-Dose Dyskinesia and Light Body Weight as Predictors of Ropinirole Patch Dose Modification in Parkinson Disease: A Multicenter Retrospective Study.

Clinical neuropharmacology·2026
Same journal

A Double-blind, Placebo-controlled Study of Lumateperone in the Treatment of Borderline Personality Disorder.

Clinical neuropharmacology·2026
Same journal

Yesterday Once More: Revisiting Catatonia in an Elderly Stroke Patient.

Clinical neuropharmacology·2026
Same journal

Overlapping Hyperosmolar Therapy in Patients With Elevated and Refractory Intracranial Pressure.

Clinical neuropharmacology·2026
See all related articles

Idiopathic hemifacial spasm, a neurovascular condition, can be triggered by vasodilation. This case study highlights how nitrates, used for chest pain, exacerbated muscle twitching in a patient with hemifacial spasm.

Area of Science:

  • Neurology
  • Neuroscience
  • Vascular Neurology

Background:

  • Hemifacial spasm is characterized by involuntary unilateral facial muscle contractions.
  • It is often caused by vascular compression of the facial nerve root.
  • Idiopathic hemifacial spasm presents a diagnostic and therapeutic challenge.

Observation:

  • An 85-year-old man with a 23-year history of idiopathic hemifacial spasm was successfully treated with botulinum toxin.
  • The patient experienced prompt exacerbation of muscle twitching upon occasional nitrate intake for precordial pain.
  • This suggests a potential link between vasodilation and hemifacial spasm exacerbation.

Findings:

  • Nitrate-induced vasodilation can trigger or worsen hemifacial spasm symptoms.
  • The neurovascular compression mechanism in hemifacial spasm may be sensitive to circulatory changes.

Related Experiment Videos

  • This exacerbation pattern provides insights into the pathophysiology of neurovascular compressive syndromes.

    • Implications:

    • Vasodilating agents may need cautious use in patients with hemifacial spasm.
    • Understanding triggers like vasodilation can refine treatment strategies for hemifacial spasm.
    • This case broadens the understanding of factors influencing neurovascular compressive conditions.