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Published on: April 13, 2010
A reason why measures to avoid mite-induced asthma are more effective in children than in adults
1Department of Pediatrics, B.C.'s Children's Hospital, Vancouver, Canada.
Insights
Children with mite-sensitive asthma show greater improvement with reduced mite allergen exposure in bedding compared to adults. This is likely due to children spending significantly more time in bed, increasing allergen exposure.
Area of Science:
- Allergy and Immunology
- Pediatric Respiratory Medicine
- Environmental Health
Background:
- Mite-sensitive asthma is a common condition, particularly in children.
- Previous observations suggest children with asthma respond better to allergen avoidance in bedrooms than adults.
- The specific reasons for this differential response require further investigation.
Purpose of the Study:
- To investigate the difference in mite allergen exposure between children and adults with mite-sensitive asthma.
- To explore the relationship between time spent in bed and allergen exposure in pediatric asthma patients.
Main Methods:
- A study of 882 children attending an allergy clinic was conducted.
- Standardized questionnaires were administered to parents.
- Skin prick tests for Dermatophagoides pteronyssinus and D. farinae were performed on children.
- Time spent in bed was recorded and analyzed based on age.
Main Results:
- Children spent a mean of 12.0 hours in bed daily, significantly longer than their parents (8.4 hours).
- Time spent in bed decreased with increasing age in children.
- Skin prick tests confirmed mite sensitivity in the pediatric population.
Conclusions:
- Children with mite-sensitive asthma experience longer daily exposure to mite allergens in bed compared to adults.
- This prolonged exposure is a likely factor contributing to the more pronounced response observed in children to allergen avoidance measures in the bedroom.
Abstract:
Mite-sensitive asthmatics seem to respond more markedly to a reduction in mite allergen in the bedding if they are children than if they are adults. In order to investigate this difference, 882 children who attended our allergy clinic were studied. The accompanying parents were asked standardized questions, and skin prick tests to Dermatophagoides pteronyssinus and D. farinae were performed on the children. The number of hours that the children spent in bed lessened progressively with increasing age, from a mean of 13.6 hrs. for 1 year olds to 9.5 hrs for 17 yr olds: the mean for the total population was 12.0 hrs. This was significantly longer than the mean for the parents, 8.4 hrs (p=.000). It is likely that a longer period of exposure to mite allergen in bed is an important reason why children respond more markedly to avoidance measures in the bedroom than adults do.
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