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Related Experiment Videos

Zenker's diverticulum

E Achkar1

  • 1Department of Gastroenterology, Cleveland Clinic Foundation, Ohio 44195, USA.

Digestive Diseases (Basel, Switzerland)
|June 9, 1998
PubMed
Summary
This summary is machine-generated.

Zenker's diverticulum, a pouch in the esophagus, is caused by poor upper sphincter compliance. Surgical intervention, primarily diverticulectomy with cricopharyngeal myotomy, is the standard treatment for this condition.

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Area of Science:

  • Gastroenterology and Surgery
  • Esophageal Disorders

Background:

  • Zenker's diverticulum is a posterior pouch above the upper esophageal sphincter in Killian's triangle.
  • Historically attributed to cricopharyngeal incoordination, current evidence suggests poor upper sphincter compliance and increased hypopharyngeal pressures are key factors.
  • Symptoms range from asymptomatic to dysphagia, regurgitation, and globus sensation as the pouch enlarges.

Purpose of the Study:

  • To review the pathophysiology, diagnosis, and treatment of Zenker's diverticulum.

Main Methods:

  • Diagnostic review focusing on barium swallow for visualization of the cricopharyngeal area.
  • Surgical treatment modalities and historical techniques.

Main Results:

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  • Barium swallow is the preferred diagnostic imaging.
  • Diverticulectomy combined with cricopharyngeal myotomy is the most common surgical approach.
  • Endoscopic treatments are less favored in the United States.

    • Conclusions:

    • Zenker's diverticulum pathogenesis involves upper esophageal sphincter dysfunction.
    • Surgical management, particularly diverticulectomy with myotomy, remains the definitive treatment.
    • Further research into the speculative link with gastroesophageal reflux is warranted.