Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Congenital diaphragmatic hernia

J C Langer1

  • 1Department of Surgery, Washington University School of Medicine, St. Louis, Missouri, USA. langerj@msnotes.wustl.edu

Chest Surgery Clinics of North America
|June 10, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Guidelines for the management of postoperative soiling in children with Hirschsprung disease.

Pediatric surgery international·2019
Same author

Guidelines for the management of postoperative obstructive symptoms in children with Hirschsprung disease.

Pediatric surgery international·2017
Same author

Minimally invasive therapy for fetal sacrococcygeal teratoma: case series and systematic review of the literature.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2014
Same author

Minimally invasive fetal therapy for hydropic lung masses: three different approaches and review of the literature.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2013
Same author

Fetal thoracoamniotic shunting for large macrocystic congenital cystic adenomatoid malformations of the lung.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2012
Same author

Does gastric dilation predict adverse perinatal or surgical outcome in fetuses with gastroschisis?

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2011
Same journal

New treatment modalities for end-stage emphysema.

Chest surgery clinics of North America·2003
Same journal

Cost effectiveness of lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Results of lung volume reduction surgery for emphysema.

Chest surgery clinics of North America·2003
Same journal

Complications after lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Operative techniques for lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Patient selection for lung volume reduction surgery.

Chest surgery clinics of North America·2003
See all related articles

Congenital diaphragmatic hernia (CDH) is a serious birth defect with high mortality due to lung issues and other anomalies. Current treatments are improving, and new innovations offer hope for affected infants.

Area of Science:

  • Pediatric Surgery
  • Neonatology
  • Developmental Biology

Background:

  • Congenital diaphragmatic hernia (CDH) is a congenital defect where abdominal organs enter the chest through a diaphragm opening.
  • The posterolateral foramen of Bochdalek is the most common site for CDH.
  • High mortality in CDH is linked to associated anomalies, pulmonary hypoplasia, and pulmonary hypertension.

Purpose of the Study:

  • To review current management strategies for congenital diaphragmatic hernia (CDH).
  • To discuss the challenges and outcomes associated with CDH.
  • To explore emerging and unproven treatments for severe CDH cases.

Main Methods:

  • Review of existing literature on CDH management.
  • Analysis of current therapeutic approaches including delayed surgical repair, pharmacologic treatments, and respiratory support (e.g., high-frequency oscillation, ECMO).

Related Experiment Videos

  • Discussion of novel and experimental therapies like permissive hypercapnia, fetal surgery, and liquid ventilation.

    • Main Results:

    • Despite various management strategies, CDH continues to have a high mortality rate.
    • Survivors of CDH often experience significant gastrointestinal and neurological morbidities.
    • Established treatments include delayed surgical repair and management of pulmonary hypertension.

    Conclusions:

    • Congenital diaphragmatic hernia (CDH) presents significant challenges in neonatal care.
    • While current treatments have advanced, outcomes remain impacted by associated conditions.
    • Future innovations hold promise for improving survival and reducing long-term morbidity in CDH patients.