Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The diaphragm in emphysema

M Ruel1, J Deslauriers, F Maltais

  • 1Thoracic Surgery Division, Centre de Penumologie de l'Hôpital Laval, Sainte-Foy, Quebec, Canada.

Chest Surgery Clinics of North America
|June 10, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erector spinae plane block did not improve postoperative pain-related outcomes and recovery after video-assisted thoracoscopic surgery : a randomised controlled double-blinded multi-center trial.

BMC anesthesiology·2024
Same author

Food systems, diets and nutrition in the wake of COVID-19.

Nature food·2023
Same author

Comparative roadmaps of reprogramming and oncogenic transformation identify Bcl11b and Atoh8 as broad regulators of cellular plasticity.

Nature cell biology·2022
Same author

Salbutamol use in relation to maintenance bronchodilator efficacy in COPD: a prospective subgroup analysis of the EMAX trial.

Respiratory research·2020
Same author

Recipients with blood group A associated with longer survival rates in cardiac valvular bioprostheses.

EBioMedicine·2019
Same author

Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study.

Thorax·2015
Same journal

New treatment modalities for end-stage emphysema.

Chest surgery clinics of North America·2003
Same journal

Cost effectiveness of lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Results of lung volume reduction surgery for emphysema.

Chest surgery clinics of North America·2003
Same journal

Complications after lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Operative techniques for lung volume reduction surgery.

Chest surgery clinics of North America·2003
Same journal

Patient selection for lung volume reduction surgery.

Chest surgery clinics of North America·2003
See all related articles

Emphysema causes diaphragm dysfunction due to hyperinflation, leading to fatigue. Treatments like pulmonary rehabilitation aim to improve diaphragm function in these patients.

Area of Science:

  • Pulmonary Medicine
  • Respiratory Physiology

Background:

  • Emphysema is characterized by lung hyperinflation.
  • Diaphragm mechanics are crucial for respiratory function.

Purpose of the Study:

  • To investigate the mechanical disadvantages of the diaphragm in emphysema.
  • To understand the impact of hyperinflation on diaphragm configuration and function.

Main Methods:

  • The study focuses on the biomechanical alterations of the diaphragm in emphysema.
  • Analysis of diaphragm position, zone of apposition, radius of curvature, and muscle fiber length.

Main Results:

  • Hyperinflation places the diaphragm in a disadvantageous position, reducing muscle fiber length and altering its mechanical arrangement.

Related Experiment Videos

  • The diaphragm in emphysema exhibits suboptimal configuration but lacks inherent structural insufficiency.
  • Increased demand from hyperinflation and airflow obstruction diminishes diaphragmatic force reserve, potentially leading to fatigue.

    • Conclusions:

    • Diaphragm dysfunction in emphysema is primarily due to mechanical disadvantage, not structural failure.
    • Imbalances in diaphragmatic performance and demand are key targets for emphysema treatment strategies.
    • Pulmonary rehabilitation and lung volume reduction surgery address diaphragmatic fatigue in emphysema.