[Functional-structural changes in the myocardium in systemic physical loading]
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Updated: Oct 29, 2026

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure
Published on: December 2, 2014
M S Hnatiuk1, V I Il'nyts'kyĭ, L A Hnatiuk
1Medical Institute, Ministry of Public Health of the Ukraine, Ternopol.
Abstract:
By means of ultrastructural and morphometrical methods hearts of 15 white rats have been studied during adaptation to the physical static load. This exercise induced the adaptive changes of the myocardium: hypertrophy and dilatation of the heart chambers. Hypertrophy of the myocardial parts takes place mainly at the expense of increasing of the length and width of cardiomyocytes. In these structures the increase of synthetic and secretive function was founded. Moderate training have improved the metabolism of the cardiomyocytes and created certain reserve of energy in the structures which were connected with the process of adaptation after the physical static load.
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