Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Childhood sarcoidosis

M S Vaphiades1, E Eggenberger

  • 1Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock 72205-7199, USA.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|June 11, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ophthalmic presentation of giant cell arteritis in African-Americans.

Eye (London, England)·2016
Same author

[We cannot care alone: volunteers in dementia care at Nürnberg General Hospital].

Zeitschrift fur Gerontologie und Geriatrie·2013
Same author

[Sacrocystis hjorti lesions in hunted red deer in Switzerland].

Schweizer Archiv fur Tierheilkunde·2012
Same author

The miller fisher syndrome: an infranuclear cause of diffuse ophthalmoplegia.

The American orthoptic journal·2010
Same author

Retinal architecture predicts pupillary reflex metrics in MS.

Multiple sclerosis (Houndmills, Basingstoke, England)·2008
Same author

Break in binocular fusion during head turning in MS patients with INO.

Neurology·2008

Sarcoidosis can affect children, causing facial palsy and hearing loss. This case highlights the importance of considering sarcoidosis in pediatric patients with neurological and ocular symptoms.

Area of Science:

  • Neurology
  • Ophthalmology
  • Pediatrics

Background:

  • Sarcoidosis is a multisystem inflammatory disease characterized by noncaseating granulomas.
  • While typically affecting adults, pediatric sarcoidosis presents unique diagnostic challenges.
  • Cranial nerve involvement, particularly facial nerve palsy, can be an early manifestation.

Observation:

  • A 10-year-old female presented with bilateral lower motor neuron facial palsy and hearing loss.
  • Brain MRI revealed enhancement of the cranial nerve VII-VIII complex.
  • Ocular findings included bilateral disc elevation and facial swelling.

Findings:

  • Parotid gland biopsy confirmed noncaseating granulomas.
  • The clinical presentation and biopsy findings were consistent with sarcoidosis.

Related Experiment Videos

Implications:

  • This case underscores the need for a high index of suspicion for sarcoidosis in children with unexplained neurological and ocular signs.
  • Early diagnosis and treatment are crucial to prevent long-term sequelae.
  • Further research into pediatric sarcoidosis is warranted to improve diagnostic and therapeutic strategies.