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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Sickle cell disease and the general surgeon

A W Meshikhes1, A A al-Faraj

  • 1Department of Surgery, Dammam Central Hospital, Eastern Province, Saudi Arabia.

Journal of the Royal College of Surgeons of Edinburgh
|June 11, 1998
PubMed

Insights

Sickle cell disease (SCD) is a genetic disorder causing anemia and pain crises. Recognizing and managing surgical issues in SCD patients is crucial due to high risks, requiring medical and surgical team collaboration.

Area of Science:

  • Hematology
  • Genetics
  • Vascular Biology

Background:

  • Sickle cell disease (SCD) is a prevalent genetic disorder with significant global health implications.
  • Characterized by chronic hemolytic anemia and vaso-occlusive crises, SCD leads to organ damage via vascular occlusion by sickled red blood cells.
  • SCD presents as a multisystem disease, posing diverse surgical challenges across various surgical specialties.

Purpose of the Study:

  • To review the spectrum of surgical problems encountered in patients with sickle cell disease.
  • To discuss the management strategies for these surgical complications in the context of SCD.
  • To emphasize the importance of recognizing surgical implications of SCD for general surgeons.

Main Methods:

  • Literature review of surgical complications in sickle cell disease patients.
  • Analysis of case studies and management approaches.
  • Synthesis of current recommendations for surgical care in SCD.

Main Results:

  • SCD patients face a wide array of surgical ailments due to the disease's multisystemic nature.
  • Surgical interventions in SCD are associated with elevated rates of morbidity and mortality.
  • Effective management necessitates close interdisciplinary collaboration between medical and surgical teams.

Conclusions:

  • The surgical management of sickle cell disease patients requires careful consideration and planning.
  • Enhanced awareness and understanding of surgical implications are vital for surgeons managing these patients.
  • Integrated care models are essential to improve outcomes for SCD patients requiring surgical intervention.

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