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[The characteristics of the DIC syndrome in gastrointestinal hemorrhages]

A V Beliaev

    Likars'Ka Sprava
    |June 11, 1998
    PubMed

    With the purpose of assessing the part DIC syndrome has in hemorrhage, blood coagulation system was studied in patients presenting with gastrointestinal hemorrhage. Thrombin, a blood coagulation IIa factor, which is one of the chief markers of DIC syndrome, has been found in great amounts in blood in 50% of cases. But this did not lead to disseminated transformation of fibrinogen to fibrin because of the action of the inhibitor of coagulation during the stage of activation of fibrinogen by thrombin. Antithrombin III had but a minor part in these processes. It is suggested that rise in concentration of thrombin that is not accompanied by formation of disseminated fibrin might be of compensatory and adaptive significance. Another characteristic of blood coagulation system in the patients is depressed plasminolysis, while increase, against this background, in concentration of products of fibrin/fibrinogen degradation that is most common, reflects disturbance in the processes of their elimination from the bloodstream.

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