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Reference ranges of reticulocytes in adults
N Charuruks1, W Limpanasithikul, N Voravud
1Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Summary
This study establishes reference values for reticulocyte count and corpuscular indices in healthy adults using an automated analyzer. These findings provide essential benchmarks for diagnosing and managing various hematological conditions.
Area of Science:
- Hematology
- Clinical Pathology
- Laboratory Medicine
Background:
- Accurate reticulocyte count and corpuscular indices are crucial for diagnosing and monitoring hematological disorders.
- Establishing reliable reference ranges is essential for interpreting these parameters in clinical practice.
Purpose of the Study:
- To determine reference values for reticulocyte count and its corpuscular indices in a healthy adult population.
- To validate the use of the Technicon H*3 RTC automated blood cell analyzer for reticulocyte analysis according to ICSH guidelines.
Main Methods:
- A cohort of 200 healthy adult blood donors (100 male, 100 female) aged 17-60 years was analyzed.
- Automated blood cell analyzer Technicon H*3 RTC was used to measure reticulocyte count and corpuscular indices (MCVr, CHCMr, CHr, RDWr, HDWr, CHDWr).
- Reference ranges were calculated using the arithmetic mean ± 2 standard deviations.
Main Results:
- Reference values and ranges were established for reticulocyte count and all measured corpuscular indices.
- The study provides a comprehensive dataset for reticulocyte parameters in a healthy adult population.
Conclusions:
- The Technicon H*3 RTC analyzer can reliably determine reticulocyte count and corpuscular indices.
- The established reference ranges serve as a valuable tool for clinical hematology laboratories.