[Evaluation of polychemotherapy of small cell lung carcinoma]

Small cell carcinoma of the lung is a separate clinical and pathological entity with characteristics of early and wide dissemination, and also great sensitivity on chemotherapy and radiotherapy. We evaluated results of therapy of patients with pathohistological verification of small cell carcinoma of the lung with use two polychemotherapy regimes (VCAV and CAP) particular or in combination with radiotherapy. We achieved the best results with application VCAV regime alone (local response 100%, complete response 78.6%, partial response 21.4%) or, in combination with radiotherapy in relation on CAP regime. Our results, when compared to experiences of foreign authors, though we evaluated it on minority series, also demonstrated better results when both regimes of polychemotherapy were used.