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[Evaluation of drugs: efficacy, applicability, effectiveness and efficiency]
M H Pronk1, G J Bonsel, M J Brorens
1Stuurgroep Gezondheidszorg, Hilversum.
Nederlands Tijdschrift Voor Geneeskunde
|June 12, 1998
Summary
A standardized drug assessment system is needed to manage rising drug costs and limited budgets. This four-step evaluation incorporates therapeutic and financial aspects for better pharmacotherapeutic policies.
Area of Science:
- Pharmacoeconomics
- Health Services Research
- Drug Evaluation
Context:
- Rising drug costs and budget constraints necessitate improved pharmacotherapeutic policy development.
- Current drug evaluation systems focus on efficacy and applicability before market approval.
- A gap exists in systematically incorporating cost-effectiveness into drug assessment.
Purpose:
- To propose a standardized, four-step assessment system for pharmacotherapeutic policy.
- To integrate both therapeutic and financial considerations into drug evaluation.
- To guide governments, institutions, researchers, prescribers, pharmacists, and industry in drug assessment.
Summary:
- The proposed system involves four successive steps: efficacy, applicability, effectiveness, and efficiency.
- Steps 1 and 2 align with current pre-market drug evaluation standards.
- Steps 3 and 4 introduce (cost) effectiveness analysis for comprehensive evaluation.
Impact:
- Implementation of this stepwise approach can lead to optimal pharmacotherapeutic outcomes.
- Requires timely adoption of existing guidelines for effective and efficient research.
- Aims to optimize resource allocation in healthcare through evidence-based drug selection.