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Pre- and postoperative growth in persistent ductus arteriosus
Archives of Disease in Childhood
|July 1, 1976
Insights
Infants with persistent ductus arteriosus under six months often experience intrauterine growth retardation. Post-ligation surgery, most infants gain weight, except for those growing towards normal or remaining small.
Area of Science:
- Pediatric Cardiology
- Neonatal Health
Background:
- Persistent ductus arteriosus (PDA) is a common congenital heart condition in neonates.
- Intrauterine growth retardation (IUGR) is a significant concern in infants with congenital heart defects.
Purpose of the Study:
- To investigate the impact of PDA ligation on infant growth trajectories.
- To identify factors influencing postoperative weight gain in infants with PDA.
Main Methods:
- Retrospective analysis of 24 infants under six months undergoing PDA ligation.
- Assessment of weight centiles before and after surgical intervention.
Main Results:
- 71% of infants showed a decline in weight centile prior to surgery.
- 84% of infants experienced postoperative weight gain.
- Infants who did not gain weight were either large-for-dates infants normalizing or small-for-dates infants remaining small.
Conclusions:
- PDA ligation in infants under six months is associated with initial growth deceleration.
- Most infants demonstrate catch-up growth post-ligation.
- Preoperative growth status (large-for-dates or small-for-dates) influences postoperative weight trajectory.
Abstract:
Children with a persistent ductus arteriosus requiring ligation under 6 months of age show evidence of intrauterine growth retardation. By the time of operation the weight centile of 17 (71%) of 24 such infants had fallen, but 20(84%) of the 24 gained weight postoperatively. Those who did not so were either large-for-dates infants growing towards the normal or small-for-dates infants who remained small postoperatively.