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Related Experiment Videos

Pre- and postoperative growth in persistent ductus arteriosus

D Pickering, V Rose, B Armstrong

    Archives of Disease in Childhood
    |July 1, 1976
    PubMed
    Summary

    Infants with persistent ductus arteriosus under six months often experience intrauterine growth retardation. Post-ligation surgery, most infants gain weight, except for those growing towards normal or remaining small.

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    Area of Science:

    • Pediatric Cardiology
    • Neonatal Health

    Background:

    • Persistent ductus arteriosus (PDA) is a common congenital heart condition in neonates.
    • Intrauterine growth retardation (IUGR) is a significant concern in infants with congenital heart defects.

    Purpose of the Study:

    • To investigate the impact of PDA ligation on infant growth trajectories.
    • To identify factors influencing postoperative weight gain in infants with PDA.

    Main Methods:

    • Retrospective analysis of 24 infants under six months undergoing PDA ligation.
    • Assessment of weight centiles before and after surgical intervention.

    Main Results:

    • 71% of infants showed a decline in weight centile prior to surgery.
    • 84% of infants experienced postoperative weight gain.
    • Infants who did not gain weight were either large-for-dates infants normalizing or small-for-dates infants remaining small.

    Conclusions:

    • PDA ligation in infants under six months is associated with initial growth deceleration.
    • Most infants demonstrate catch-up growth post-ligation.
    • Preoperative growth status (large-for-dates or small-for-dates) influences postoperative weight trajectory.

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