Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Emergency open lung biopsy

J M Nelems, J D Cooper, R D Henderson

    The Annals of Thoracic Surgery
    |September 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Spinal manifestations of CLN1 disease start during the early postnatal period.

    Neuropathology and applied neurobiology·2020
    Same author

    CRISPR/Cas9 mediated generation of an ovine model for infantile neuronal ceroid lipofuscinosis (CLN1 disease).

    Scientific reports·2019
    Same author

    Desmopressin stimulation testing: Response to intravenous and intranasal forms.

    Haemophilia : the official journal of the World Federation of Hemophilia·2018
    Same author

    Serum proteomic profiles of depressive subtypes.

    Translational psychiatry·2016
    Same author

    Serum biomarkers predictive of depressive episodes in panic disorder.

    Journal of psychiatric research·2015
    Same author

    Development of a blood-based molecular biomarker test for identification of schizophrenia before disease onset.

    Translational psychiatry·2015
    Same journal

    Late outcomes of postoperative complete heart block after congenital heart surgery: recovery or re-heart block?

    The Annals of thoracic surgery·2026
    Same journal

    Coronary artery bypass grafting based on computed tomography-derived fractional flow reserve versus angiography: Early results.

    The Annals of thoracic surgery·2026
    Same journal

    Beyond R0: Margin Cytology and Local Control After Sublobar Resection.

    The Annals of thoracic surgery·2026
    Same journal

    Deferred AVR During CABG in Moderate Aortic Stenosis: Lower Index Risk or Deferred Cumulative Risk?

    The Annals of thoracic surgery·2026
    Same journal

    The Renaissance of Transapical TAVR: From Competing Access Route to Enabling Platform for Hybrid Heart Therapy.

    The Annals of thoracic surgery·2026
    Same journal

    A Moving Target: Interpreting Post-TAVI Reintervention in a Rapidly Evolving Era.

    The Annals of thoracic surgery·2026
    See all related articles

    Emergency open lung biopsy is a valuable diagnostic tool for patients in respiratory failure. This procedure accurately diagnosed conditions in 96% of cases, enabling life-saving therapy.

    Area of Science:

    • Pulmonology
    • Thoracic Surgery
    • Critical Care Medicine

    Background:

    • Patients with rapidly deteriorating respiratory failure often require urgent diagnosis.
    • Open lung biopsy is an invasive procedure with potential risks.

    Purpose of the Study:

    • To evaluate the diagnostic yield and clinical impact of emergency open lung biopsy.
    • To determine if thrombocytopenia or PEEP ventilation are contraindications.

    Main Methods:

    • Retrospective review of 28 emergency open lung biopsies.
    • Analysis of pre-biopsy clinical diagnosis accuracy.
    • Assessment of post-biopsy specific therapy and outcomes.

    Main Results:

    • 96% diagnostic accuracy (27/28 patients).

    Related Experiment Videos

  • Pre-biopsy diagnosis was incorrect or incomplete in 55% (15/28).
  • Specific therapy guided by biopsy was lifesaving in 12/28 patients.
  • Conclusions:

    • Emergency open lung biopsy is highly effective in establishing diagnoses in critically ill patients.
    • The diagnostic value and lifesaving potential outweigh the procedural risks.
    • Thrombocytopenia and PEEP ventilation are not absolute contraindications.