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Related Experiment Videos

Small renal cell carcinoma: MRI with pathologic correlation

H Shinmoto1, Y Yuasa, A Tanimoto

  • 1Department of Diagnostic Radiology, Keio University School of Medicine, Tokyo, Japan. shinmoto@ga2.so-net.or.jp

Journal of Magnetic Resonance Imaging : JMRI
|June 17, 1998
PubMed
Summary
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Magnetic resonance imaging (MRI) reveals distinct features of small renal cell carcinomas (RCCs). Papillary RCCs often exhibit a T2-hypointense appearance, potentially linked to hemosiderin deposition or hemorrhage.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Small renal cell carcinomas (RCCs) require accurate diagnostic methods.
  • Magnetic resonance imaging (MRI) is a key imaging modality for evaluating renal masses.
  • Histopathological classification is crucial for RCC diagnosis and treatment.

Purpose of the Study:

  • To correlate MRI features of small renal cell carcinomas (RCCs) with their histological subtypes.
  • To identify specific MRI signal intensities associated with different RCC histological types.

Main Methods:

  • Retrospective review of MRI features (T1- and T2-weighted images) in 24 patients with small RCCs.
  • Classification of MRI signal intensities (hypointensity, isointensity, hyperintensity).
  • Histopathological classification of RCCs into alveolar, papillary, tubular, and cystic types.

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Main Results:

  • Alveolar tumors showed T1 hypointensity to isointensity and T2 isointensity to hyperintensity.
  • Papillary tumors consistently demonstrated T2 hypointensity.
  • T2 hypointensity was associated with hemosiderin deposition, hemorrhage, and necrosis in most cases, but also observed in papillary RCCs without these findings.

Conclusions:

  • Papillary renal cell carcinoma (RCC) is associated with a T2-hypointense appearance on MRI.
  • T2-hypointense findings in small RCCs can be attributed to hemosiderin deposition, hemorrhage, and necrosis.
  • The T2-hypointense appearance may be an independent imaging feature of papillary RCC.