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Changing definition of glaucoma

R Bathija1, N Gupta, L Zangwill

  • 1Department of Ophthalmology, University of California, San Diego, La Jolla 92093-0946, USA.

Journal of Glaucoma
|June 17, 1998
PubMed
Summary
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Definitions for open-angle glaucoma (OAG) lack consistency in research. While recent studies offer more specific criteria, a consensus definition for OAG is needed.

Area of Science:

  • Ophthalmology
  • Clinical Research Methodology

Background:

  • The definition of open-angle glaucoma (OAG) is crucial for consistent clinical research.
  • Previous studies indicate variability in OAG diagnostic criteria.

Purpose of the Study:

  • To assess changes in the definition of open-angle glaucoma (OAG) within peer-reviewed literature over a 15-year period.
  • To analyze the evolution of optic nerve, visual field, and intraocular pressure (IOP) criteria used in OAG definitions.

Main Methods:

  • A literature review of OAG articles from major ophthalmology journals (1980-1995) was conducted.
  • 182 articles were analyzed to identify and classify the criteria used for defining OAG.
  • Studies were categorized by design, glaucoma severity, and type.

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Main Results:

  • 66% of reviewed articles defined OAG, with varied criteria usage.
  • The 1990s saw an increase in specific optic disc and visual field criteria compared to the 1980s.
  • Intraocular pressure (IOP) remained a consistent sole criterion, while prospective studies more frequently provided specific definitions.

Conclusions:

  • Current clinical research exhibits a lack of consistent definitions for open-angle glaucoma (OAG).
  • Despite improvements in specificity in recent studies, a consensus definition for OAG is still required.
  • Standardizing OAG definitions will enhance the reliability and comparability of glaucoma research.