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Updated: Aug 17, 2026

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Published on: December 8, 2010
Changes in skin blood flow over the foot with warming of the contralateral heel
S Dollberg1, H Atherton, S Hoath
1Department of Neonatology, Lis Maternity Hospital, Tel Aviv, Israel.
Insights
Warming the opposite leg of preterm infants does not improve blood flow to the affected leg. This study found no significant difference in skin blood flow, challenging the practice of using heat to treat vasospasm from umbilical artery catheterization.
Area of Science:
- Neonatal physiology
- Vascular medicine
- Pediatric critical care
Background:
- Umbilical artery catheterization (UAC) is common in preterm infants.
- UAC can lead to leg vasospasm, a serious complication.
- Current practice involves warming the contralateral leg to promote blood flow.
Purpose of the Study:
- To investigate if heating the contralateral extremity induces reflex vasodilation in preterm infants.
- To determine if this intervention increases peripheral blood flow to the affected limb.
Main Methods:
- Ten stable preterm infants (no UAC for 2 weeks) were studied.
- Laser Doppler was used to measure skin perfusion in the distal leg.
- The contralateral foot was heated to 40.5°C, measuring blood flow before and after.
Main Results:
- No significant difference in skin blood flow was observed between conditions.
- Heating the contralateral foot did not induce reflex vasodilation in the contralateral foot.
Conclusions:
- Direct heat application to one extremity does not induce contralateral reflex vasodilation in preterm infants.
- The practice of warming the opposite leg to treat UAC-related vasospasm may not be effective.
Abstract:
Vasospasm in one leg is a common complication of umbilical artery catheterization in preterm infants. It is a common practice to wrap the contralateral leg in a warm washcloth. The rationale for this intervention is to induce reflex vasodilatation of the affected extremity, thereby avoiding the necessity to remove or replace the catheter. This study tested the hypothesis that heating the contralateral extremity in preterm infants would increase peripheral blood flow to the contralateral foot. Ten stable preterm infants who had had no umbilical catheter inserted for at least 2 weeks were studied. Skin perfusion was measured using the laser Doppler method in the distal leg after heating of the opposite foot to 40.5 degrees C. Blood flow to the skin of the contralateral foot was measured before and after warming the ipsilateral one. The skin blood flow measured with and without heat application to the contralateral foot was not significantly different. Direct heat does not induce contralateral reflex vasodilatation in the foot of preterm infants.
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