Related Experiment Video
Updated: Aug 4, 2026

Isolation of Lymphocytes from Mouse Genital Tract Mucosa
Published on: September 3, 2012
Antisperm antibodies and microorganisms in genital secretions--a clinically significant relationship?
W Eggert-Kruse1, G Rohr, S Probst
1Department of Gynecological Endocrinology and Reproductive Medicine, Women's Hospital Heidelberg, Germany.
Abstract:
In asymptomatic infertility patients, no significant relationship was found between the presence of antisperm antibodies (ASA) in serum and in semen samples (IgG and/or IgA ASA), differentiated with the mixed antiglobulin reaction (MAR), and the microbial colonization of ejaculates covering a broad spectrum of microorganisms. Likewise, there was no significant association of ASA with microbial findings in patients' female partners, who also presented without symptoms of genital tract infection and were screened at the same time. Furthermore, ASA in semen (IgG and IgA) were not significantly related to several potential markers of subclinical male sexual gland infection or inflammation (leukocytes, PMN elastase, albumin, C3c) evaluated in aliquots of the same ejaculates used for immunological testing.
Related Concept Videos
Spermatogenesis
Surface Membrane Barriers
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
Microbiota of the Urogenital Tract
Genital Herpes
Amebiasis
Trichomoniasis

