Evaluating agreement with a gold standard in method comparison studies
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1Department of Mathematics and Statistics, Northern Arizona University, Flagstaff 86011-5717, USA. Roy.St.Laurent@nau.edu
Abstract:
We develop a statistical model for method comparison studies where a gold standard is present and propose a measure of agreement. This measure can be interpreted as a population correlation coefficient in a constrained bivariate model. An estimator of this coefficient is proposed and its statistical properties explored. Applications of the new methodology to data from the medical literature are presented.
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