Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Extramedullary anaplastic plasmacytoma]

M Veiga González¹, M F Fresno Forcelledo, M J Pérez del Río

¹Servicio de Anatomía Patológica, Hospital Central de Asturias (Hospital Covadonga), Universidad de Oviedo.

Anales De Medicina Interna (Madrid, Spain : 1984)

|June 18, 1998

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hepatobiliary and Pancreatic: Sertraline-induced vanishing bile duct syndrome treated with plasmapheresis.

Journal of gastroenterology and hepatology·2018

Same author

Cutaneous mucormycosis infection by Absidia in two consecutive liver transplant patients.

Transplantation proceedings·2012

Same author

[Spinal section due to a C7 vertebral body fracture].

Anales de pediatria (Barcelona, Spain : 2003)·2010

Same author

[Brain metastasis caused by colorectal carcinoma].

Revista espanola de enfermedades digestivas·2009

Same author

[Persistent vena hemiazygos and absence of intrahepatic inferior vena cava. A casual finding?].

Anales de pediatria (Barcelona, Spain : 2003)·2008

Same author

[Left ventricle pseudoaneurysm following myocardial infarction: MRI findings].

Anales de medicina interna (Madrid, Spain : 1984)·2006

Same journal

[Giant cell arteritis: and uncommon cause of chronic cough].

Anales de medicina interna (Madrid, Spain : 1984)·2009

Same journal

[Pneumonia and lumbar spondylodiscitis as complications of Staphylococcus aureus's bacteriemia].

Anales de medicina interna (Madrid, Spain : 1984)·2009

Same journal

[Review of eleven cases of erythema induratum at a second level hospital].

Anales de medicina interna (Madrid, Spain : 1984)·2009

Same journal

[Primary bacteremias caused by Pasteurella multocida].

Anales de medicina interna (Madrid, Spain : 1984)·2009

Same journal

[Primary pulmonary lymphoma: an infrequent cause of pulmonary mass].

Anales de medicina interna (Madrid, Spain : 1984)·2009

Same journal

[Drugs and serotonin syndrome].

Anales de medicina interna (Madrid, Spain : 1984)·2009

See all related articles

A rare case of extramedullary plasmacytoma in the maxillary sinus was identified. This locally aggressive tumor mimicked adenocarcinoma but was confirmed via immunohistochemistry and light chain restriction, ruling out multiple myeloma.

Area of Science:

Oncology
Pathology
Head and Neck Cancer

Background:

Extramedullary plasmacytomas are rare plasma cell neoplasms occurring outside the bone marrow.
Maxillary sinus involvement is uncommon, presenting diagnostic challenges.
Distinguishing these from carcinomas is crucial for appropriate treatment.

Observation:

A 65-year-old male presented with a locally aggressive maxillary sinus mass.
Initial clinical suspicion was adenocarcinoma.
Pathological examination revealed anaplastic morphology with limited plasmacytic differentiation.

Findings:

Immunohistochemistry showed a lack of cytokeratins and epithelial membrane antigen (EMA).
Light chain restriction confirmed plasmacytic origin.

Related Experiment Videos

Absence of multiple myeloma criteria supported the diagnosis of extramedullary plasmacytoma.

Implications:

Accurate diagnosis of extramedullary plasmacytoma is vital for treatment planning.
Immunohistochemistry plays a key role in differentiating from epithelial malignancies.
This case highlights the importance of comprehensive pathological evaluation in challenging head and neck lesions.